SAT-086 CXCR4 mediates tubular epithelial cells to aggravate renal fibrosis via JAK/STAT/GSK3β/β-catenin pathway
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چکیده
منابع مشابه
Parathyroid hormone induces epithelial-to-mesenchymal transition via the Wnt/β-catenin signaling pathway in human renal proximal tubular cells.
Epithelial-to-mesenchymal transition (EMT) has been shown to play an important role in renal fibrogenesis. Recent studies suggested parathyroid hormone (PTH) could accelerate EMT and subsequent organ fibrosis. However, the precise molecular mechanisms underlying PTH-induced EMT remain unknown. The present study was to investigate whether Wnt/β-catenin signaling pathway is involved in PTH-induce...
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ژورنال
عنوان ژورنال: Kidney International Reports
سال: 2020
ISSN: 2468-0249
DOI: 10.1016/j.ekir.2020.02.093